Biopolym. Cell. 2012; 28(4):288-291.
http://dx.doi.org/10.7124/bc.000060
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Miniature as a hypothetical regulatory protein of the Bursicon/Rickets signaling cascade in the wing epithelia of Drosophila melanogaster
1, 3Bilousov O. O., 1, 2Katanaev V. L., 3Kozeretska I. A.
  1. Department of Pharmacology and Toxicology, University of Lausanne
    27, Bugnon Str., CH-1005 Lausanne, Switzerland
  2. Institute of Protein Research, Russian Academy of Sciences
    Pushchino, Moscow Region, Russian Federation, 142290
  3. Educational and Scientific Center "Institute of Biology",
    Taras Shevchenko National University of Kyiv
    64/13, Volodymyrska Str., Kyiv, Ukraine, 01601

Abstract

Soon after eclosion, epithelial cells of the Drosophila wing undergo a number of the processes due to a release of the neurohormone bursicon and its further binding to the GPCR Rickets, collectively referred to as wing maturation. Here we propose hypothetical models of the interaction between extracellular Miniature, and also Dusky, proteins and proteins responsible for triggering of the wing maturation processes in Drosophila melanogaster.
Keywords: bursicon, Rickets, Miniature, Dusky, wing maturation
Full text: (PDF, in English)

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