Biopolym. Cell. 2007; 23(3):172-187.
Mutagenesis induced by integration processes and evolution of nuclear genome
- Institute of Molecular Biology and Genetics, NAS of Ukraine
150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
Abstract
Mutational variability induced by large-scale reorganizations of genetic material such as MGE transpositions, integration or disintegration of exogenous nucleotide sequences of viral and non-viral origin, changes in chromosome set or individual chromosomes, chromatin diminution and its role in the evolution of nuclear genome are discussed.
Keywords: mutagenesis, evolution, nuclear genome, heterochromatin, mobile genetic elements, chromosome, chromatin diminution
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