Biopolym. Cell. 2007; 23(1):54-59.
http://dx.doi.org/10.7124/bc.000756
Bioinformatics
Phylogenetic analysis of structural preconditions of autogenous control of gene expression of rplJL operon at the translation level in γ-proteobacteria
1Kroupskaya I. V., 2Paton E. B.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
  2. Institute of Cell Biology and Genetic Engineering, NAS of Ukraine
    148, Akademika Zabolotnogo Str., Kyiv, Ukraine, 03680

Abstract

Phylogenetic analysis of structural preconditions of autogenous control regulation of gene expression of rplJL operon at the translation level in γ-proteobacteria has been performed. The structural preconditions of both L10 ribosomal protein and its RNA targets, which determine the possibility and the specificity of L10-RNA interaction have been studied. Phylogenetic comparison provides evidence for similarity of structural preconditions of the feedback regulation mechanism inγ-proteobacteria and Escherichia coli, except for the endosimbionts.
Keywords: autogenous control, gene expression, L10 ribosomal protein, mRNA, interaction site
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