Biopolym. Cell. 2006; 22(6):458-467.
http://dx.doi.org/10.7124/bc.00074D
Molecular Biophysics
Physical factors of collagen triple helix stability
1Boryskina O. P., 1Bolbukh T. V., 1Semenov M. A., 1Maleev V. Ya.
  1. A. Usikov Institute of Radio Physics and Electronics, NAS of Ukraine
    12, Proskura Str., Kharkov, Ukraine, 61085

Abstract

In the present study a complex approach of a number of expe­rimental techniques, namely infrared spectroscopy, quartz piezogravimetry, and differential scanning calorimetry, was used to estimate the hydration energy and enthalpy of interpeptide hydrogen bonds. On the basis of the results obtained the values of relative contributions of energies of interactions of different types into the total energy of stabilization of triple helical collagen structures were evaluated.
Keywords: collagen, poly (Gly-Pro-Pro), hydration energy, enthalpy of hydrogen bonds, infrared spectroscopy.
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