Biopolym. Cell. 2005; 21(1):12-27.
Protein S-100: structural and functional properties and role in nervous tissue
1Nikandrov V. N., 1Chaplinskaya E. V.
  1. Institute of Physiology , NAS of Belarus
    28, Academicheskaya Str., Minsk, Belarus, 220072


The literature data are analyzed concerning the classification, techniques of isolation, physical and chemical properties, locali­zation in neuronal structures, dynamics in ontogenesis, mechanisms of action and functional role in the nervous system, neurotrophic properties, and involvement of Ca2+ -binding proteins S-100 in the pathogenesis of some diseases. The contribution of S-100 to the cellular and general intersystem mechanisms of life maintenance and adaptive activity in human and animal organisms is discussed
Keywords: S-100, nervous system, structure, functions, Ca2+


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