Biopolym. Cell. 1986; 2(3):152-153.
http://dx.doi.org/10.7124/bc.0001AD
Short Communications
Effect of cell culture of Polyscias filicifollia bailey biomass on the activity of tRNA and aminoacyl-tRNA synthetase from the rabbit liver
1, 2Slavinskene R. Yu., 2Lukosevicius L. Yu., 1Kunakh V. A., 3Slepyan L. I., 1Kovalenko M. I., 2Ivanov L. L.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR
  2. Medical Institute Kaunas
    Kaunas, USSR
  3. Chemopharmaceutic Institute
    Leningrad, USSR

Abstract

The activity of tRNA and aminoacyl-tRNA synthetase from the rabbit liver is studied 6 hs after experimental myocardial infarction under the per os administration of the cell culture of Polyscias filicifolia Bailey biomass to the animals before operation. The level of aminoacylation of tRNA with leucine and the leucyl-tRNA synthetase activity in the total enzyme preparation increase in comparison with the preparations from untreated animals. The administration of P. filicifolia Baily to control (unoperated) rabbits has no effect on the tRNA acceptor activity while leucyl-tRNA synthetase activity slightly increases.
Full text: (PDF, in Russian)

References

[1] Lukoshiavichius LIu, Rodovichius GA, Kovalenko MM, PivoriunaД­te II, Prashkiavichius AK. tRNA and aminoacyl-tRNA synthetases from the liver of rabbits in experimental myocardial infarction. Vopr Med Khim. 1983;29(4):65-9.
[2] Slepyan LI, Mikhaylova NV, Kublashvili TsG. Structure roots Polyscias filicifolia Bailey. Rastitel'nyye resursy. 1978; 14:100-106
[3] Toleikis A, Dzeja P, Praskevicius A, Jasaitis A. Mitochondrial functions in ischemic myocardium. I. Proton electrochemical gradient, inner membrane permeability, calcium transport and oxidative phosphorylation in isolated mitochondria. J Mol Cell Cardiol. 1979;11(1):57-76.
[4] Demidov SV, Kovalenko MI, El'skaia AV. Biological activity of hepatic transfer RNA of rabbits of different ages. Nauchnye Doki Vyss Shkoly Biol Nauki. 1980;(12):18-24.