Biopolym. Cell. 1986; 2(3):147-149.
Short Communications
The third site of the 70S ribosome for aminoacyl-tRNA analogue binding
2Dorokhov D. B., 1Board S. B., 2Semenkov Yu. P.
  1. Department of Plant Genetics, Academy of Sciences of the Moldavian SSR
    Kishinev, USSR
  2. B. P. Konstantinov Institute of Nuclear Physics, Academy of Sciences of the USSR
    Gatchina, Leningrad distr., USSR

Abstract

The interaction of the stable aminoacyl-tRNA analogue, tRNAPhe—C—C—A(3'NH)•Phe, with 70S ribosome is studied. It is shown that in the presence of poly(U) a ribosome can bind three molecules of tRNAPhe—C—C—A(3'NH)•Phe. The «additional» site for binding aminoacyl-tRNA analogue was shown to be similar to the ribosomal E-site for deacylate tRNA.

References

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