Biopolym. Cell. 2003; 19(2):113-132.
Our "Shagreen leather" is our problem. And we have to solve it
1Kordyum V. A.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


One of the main problems to be solved by modern biology is disclosing a complex of mechanisms determining absolute reliability of both the restriction of any organism (including human) lifetime, and the existence of practically immortal life (if taken as a continuous chain of unconditionally mortal generations). A planned series of four publications is aimed at the formulation of basic ideas to develop the problem conception. The essentials allowing to regard a cell as a typical (though very complex and perfect) molecular machine, and an organism – as a self-organizing system of such molecular machines, are analyzed in the first publication.


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