Biopolym. Cell. 2002; 18(5):442-444.
http://dx.doi.org/10.7124/bc.000624
Molecular Biomedicine
Changes in the NCAM concentration in the brain neocortex frontal zone under active-defend skill conditioning
1Drozdov A. L., 1Dzyak L. A., 2Chornaya V. I.
  1. Dnipropetrovs'k State Medical Academy
    9, Dzerzhyinskoho Str., Dnipropetrovs'k, Ukraine, 49044
  2. Dnipropetrovsk National University
    72, Gagarin Av., Dnipropetrovs'k, Ukraine, 49050

Abstract

The data on changes in the neural cell adhesion molecules (NCAM) concentration in the neocortex frontal zone of the rat brain under active-defend skill conditioning are presented. The elevation of NCAM level on days 3, 7, 14, 21 and 30 after training was shown. The data suggest the NCAM participation in the neural plasticity connected with learning and memorization.
Full text: (PDF, in Russian)

References

[1] Bock E, Jorgensen OS. Rat brain synaptic vesicles and synaptic plasma membranes compared by crossed immunoelectrophoresis. FEBS Lett. 1975;52(1):37-9.
[2] Fields RD, Itoh K. Neural cell adhesion molecules in activity-dependent development and synaptic plasticity. Trends Neurosci. 1996;19(11):473–80.
[3] Walsh FS, Doherty P. Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. Annu Rev Cell Dev Biol. 1997;13:425-56.
[4] Basic Neurochemistry. Eds J. Siegel, B. Agranoff. New York: Lippincott Williams and Wilkins, 1999. 1184 p.
[5] Konorski J. Integrative activity of the brain. University of Chicago Press, 1967. 531 p.
[6] Neurochemistry. Eds IP Ashmarin, PV Stukalova. M.: Izd Inst Biomed. CHem RAMS. 1996; 470 p.
[7] Borodkin YuS, Krauz VA. Pharmacology of short-term memory, M.: Meditsina, 1978; 232 p.
[8] Kruglikov RI. Neurochemical mechanisms of learning and memory. M.: Nauka, 1981; 211 p.
[9] Ibsen S, Berezin V, N?rgaard-Pedersen B, Bock E. Enzyme-Linked Immunosorbent Assay of the D2-Glycoprotein. J Neurochem. 1983;41(2):356–62.
[10] Plokhinskiy NA. Biometry. Moscow, Mosk. Univ. Press, 1970; 367 p.
[11] J?rgensen OS, M?ller M. Immunocytochemical demonstration of the D2 protein in the presynaptic complex. Brain Res. 1980;194(2):419-29.