Biopolym. Cell. 2002; 18(1):37-47.
Reviews
Avian endogenous retroviruses: structure, expression and evolution
1Borisenko L. G., 1Rynditch A. V.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680

Abstract

The recent data about the diversity ofavian endogenous retroviruses, their structure, peculiarity of the expression and possible ways of their evolution have been analysed in the present review. A role of endogenous retroviruses in the ontogenesis and pathology development has been shown.

References

[1] Herniou E, Martin J, Miller K, Cook J, Wilkinson M, Tristem M. Retroviral diversity and distribution in vertebrates. J Virol. 1998;72(7):5955-66.
[2] Chen ZQ, Ritzel RG, Lin CC, Hodgetts RB. Sequence conservation in avian CR1: an interspersed repetitive DNA family evolving under functional constraints. Proc Natl Acad Sci U S A. 1991;88(13):5814-8.
[3] Gudkov AV, Komarova EA, Nikiforov MA, Zaitsevskaya TE. ART-CH, a new chicken retroviruslike element. J Virol. 1992;66(3):1726-36.
[4] Tikhonenko AT, Lomovskaya OL. Avian endogenous provirus (ev-3) env gene sequencing: implication for pathogenic retrovirus origination. Virus Genes. 1990;3(3):251-8.
[5] Geryk J, Dez?l?e P, Barnier JV, Svoboda J, Nehyba J, Karakoz I, Rynditch AV, Yatsula BA, Calothy G. Transduction of the cellular src gene and 3' adjacent sequences in avian sarcoma virus PR2257. J Virol. 1989;63(2):481-92.
[6] Yatsula BA, Geryk J, Briestanska J, Karakoz I, Svoboda J, Rynditch AV, Calothy G, Dez?l?e P. Origin and evolution of the c-src-transducing avian sarcoma virus PR2257. J Gen Virol. 1994;75 ( Pt 10):2777-81.
[7] Venugopal K. Avian leukosis virus subgroup J: a rapidly evolving group of oncogenic retroviruses. Res Vet Sci. 1999;67(2):113-9.
[8] Robinson HL, Astrin SM, Senior AM, Salazar FH. Host Susceptibility to endogenous viruses: defective, glycoprotein-expressing proviruses interfere with infections. J Virol. 1981;40(3):745-51.
[9] Crittenden LB, Fadly AM, Smith EJ. Effect of endogenous leukosis virus genes on response to infection with avian leukosis and reticuloendotheliosis viruses. Avian Dis. 1982;26(2):279-94.
[10] Kuhnlein U, Fairfull RW, Gowe R, Kulenkamp A, Mou L, Zadworny D. Synergism between the endogenous viral loci ev6 and ev9 in inducing immunological tolerance to avian leukosis virus. Br Poult Sci. 1993;34(1):93-104.
[11] Astrin SM. Endogenous viral genes of the White Leghorn chicken: common site of residence and sites associated with specific phenotypes of viral gene expression. Proc Natl Acad Sci U S A. 1978;75(12):5941-5.
[12] Hughes SH, Payvar F, Spector D, Schimke RT, Robinson HL, Payne GS, Bishop JM, Varmus HE. Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases. Cell. 1979;18(2):347-59.
[13] Astrin SM, Robinson HL, Crittenden LB, Buss EG, Wyban J, Hayward WS. Ten genetic loci in the chicken that contain structural genes for endogenous avian leukosis viruses. Cold Spring Harb Symp Quant Biol. 1980;44 Pt 2,:1105-9.
[14] Hughes SH, Toyoshima K, Bishop JM, Varmus HE. Organization of the endogenous proviruses of chickens: implications for origin and expression. Virology. 1981;108(1):189-207.
[15] Hughes SH, Vogt PK, Bishop JM, Varmus HE. Endogenous proviruses of random-bred chickens and ring-necked pheasants: analysis with restriction endonucleases. Virology. 1981;108(1):222-9.
[16] Coffin JM, Tsichlis PN, Conklin KF, Senior A, Robinson HL. Genomes of endogenous and exogenous avian retroviruses. Virology. 1983;126(1):51-72.
[17] Groudine M, Eisenman R, Weintraub H. Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation. Nature. 1981;292(5821):311-7.
[18] Gudkov AV, Chernov MV, Tikhonenko AT, Obukh IB, Hloz?nek I. Methylation of endogenous proviruses of Brown Leghorn chickens. Folia Biol (Praha). 1986;32(1):73-7.
[19] Rovigatti UG, Astrin SM. Avian endogenous viral genes. Curr Top Microbiol Immunol. 1983;103:1-21.
[20] Crittenden LB, Salter DW. Spontaneous mobility of subgroup a avian leukosis virus pro viruses in the genome of the chicken. Avian Pathol. 1998;27(sup1):S26-S35.
[21] Tereba A, Astrin SM. Chromosomal localization of ev-1, a frequently occurring endogenous retrovirus locus in white Leghorn chickens, by in situ hybridization. J Virol. 1980;35(3):888-94.
[22] Gudkov AV, Obukh IB, Serov SM, Naroditsky BS. Variety of endogenous proviruses in the genomes of chickens of different breeds. J Gen Virol. 1981;57(Pt 1):85-94.
[23] Hayward WS, Braverman SB, Astrin SM. Transcriptional products and DNA structure of endogenous avian proviruses. Cold Spring Harb Symp Quant Biol. 1980;44 Pt 2,:1111-21.
[24] Tereba A. Asymmetric chromosomal distribution of endogenous retrovirus loci in chickens and mice. Curr Top Microbiol Immunol. 1983;107:29-50.
[25] Baker B, Robison H, Varmus HE, Bishop JM. Analysis of endogenous avian retrovirus DNA and RNA: viral and cellular determinants of retrovirus gene expression. Virology. 1981;114(1):8-22.
[26] Benkel BF, Perreault J, Gagnon C, Conklin K. A rapid PCR-based test for the endogenous viral element ev3 of chickens. Anim Genet. 1995;26(3):189-91.
[27] Grunder AA, Benkel BF, Chambers JR, Sabour MP, Gavora JS. Characterization of eight endogenous viral (ev) genes of meat chickens in semi-congenic lines. Poult Sci. 1995;74(9):1506-14.
[28] Gudkov AV, Korec E, Chernov MV, Tikhonenko AT, Obukh IB, Hloz?nek I. Genetic structure of the endogenous proviruses and expression of the gag gene in Brown Leghorn chickens. Folia Biol (Praha). 1986;32(1):65-72.
[29] Robinson HL, Eisenman R, Senior A, Ripley S. Low freqeuncy production of recombinant subgroup E avian leukosis viruses by uninfected V-15B chicken cells. Virology. 1979;99(1):21-30.
[30] Crittenden LB, Astrin SM, Smith EJ. Independent segregation of ev 10 and ev 11, genetic loci for spontaneous production of endogenous avian retroviruses. Virology. 1983;129(2):514-6.
[31] Coffin J. Endogenous viruses. RNA tumor viruses. New York, 1984: 1109-203.
[32] Smith EJ, Bizub D, Scholl DR, Skalka AM. Characterization of a solitary long terminal repeat of avian endogenous virus origin. Virology. 1984;134(2):493-6.
[33] Benkel BF, Smith EJ. Research note: a rapid method for the detection of the Rous-associated endogenous solitary long terminal repeat, ev15. Poult Sci. 1993;72(8):1601-5.
[34] Humphries EH, Danhof ML, Hlozanek I. Characterization of endogenous viral loci in five lines of white Leghorn chickens. Virology. 1984;135(1):125-38.
[35] Gorbovitskaia M, Coville JL, Tixier-Boichard M. Molecular characterization of endogenous viral genes of the avian leukosis virus family in an experimental population of brown-egg layers. Poult Sci. 1998;77(4):605-14.
[36] Smith EJ, Crittenden LB. Genetic cellular resistance to subgroup E avian leukosis virus in slow-feathering dams reduces congenital transmission of an endogenous retrovirus encoded at locus ev21. Poult Sci. 1988;67(12):1668-73.
[37] Tixier-Boichard M, Boulliou-Robic A, Morisson M, Coquerelle G, Horst P, Benkel B. A deleted retroviral insertion at the ev21-K complex locus in Indonesian chickens. Poult Sci. 1997;76(5):733-42.
[38] Levin I, Smith EJ. Association of a chicken repetitive element with the endogenous virus-21 slow-feathering locus. Poult Sci. 1991;70(9):1948-56.
[39] Ziemiecki A, Kr?mer G, Mueller RG, H?la K, Wick G. ev 22, a new endogenous avian leukosis virus locus found in chickens with spontaneous autoimmune thyroiditis. Arch Virol. 1988;100(3-4):267-71.
[40] Gudkov AV, Serov SM, Obukh IB, Naroditski? BS. New endogenous proviruses in the genome of brown Leghorn chickens. Vopr Virusol. 1981;(2):225-8.
[41] Gudkov AV, Kolobkov SL, Obukh IB, Serov SM, Chernov MV. Structural diversity of endogenous proviruses in genomes of vertebrates. Vestn Akad Med Nauk SSSR. 1984;(5):3-9.
[42] Chernov MV, Gudkov AV, Obukh IB. Variations of endogenous chicken proviruses: characterization of new loci of endogenous proviruses in the genome of Italian partridge chickens. Folia Biol (Praha). 1984;30(5):342-8.
[43] Aarts HJ, Van Der Hulst-Van Arkel MC, Beuving G, Leenstra FR. Variations in endogenous viral gene patterns in White Leghorn, medium heavy, White Plymouth Rock, and Cornish Chickens. Poult Sci. 1991;70(6):1281-6.
[44] Sabour MP, Chambers JR, Grunder AA, Kuhnlein U, Gavora JS. Endogenous viral gene distribution in populations of meat-type chickens. Poult Sci. 1992;71(8):1259-70.
[45] Iraqi F, Soller M, Beckmann JS. Distribution of endogenous viruses in some commercial chicken layer populations. Poult Sci. 1991;70(4):665-79.
[46] Grunder AA, Benkel BF, Chambers JR, Sabour MP, Gavora JS, Dickie JW. Characterization of four endogenous viral genes in semi-congenic lines of meat chickens. Poult Sci. 1999;78(6):873-7.
[47] Nikiforov MA, Gudkov AV. ART-CH: a VL30 in chickens? J Virol. 1994;68(2):846-53.
[48] Boyce-Jacino MT, Resnick R, Faras AJ. Structural and functional characterization of the unusually short long terminal repeats and their adjacent regions of a novel endogenous avian retrovirus. Virology. 1989;173(1):157-66.
[49] Dunwiddie C, Faras AJ. Presence of retrovirus reverse transcriptase-related gene sequences in avian cells lacking endogenous avian leukosis viruses. Proc Natl Acad Sci U S A. 1985;82(15):5097-101.
[50] Dunwiddie CT, Resnick R, Boyce-Jacino M, Alegre JN, Faras AJ. Molecular cloning and characterization of gag-, pol-, and env-related gene sequences in the ev- chicken. J Virol. 1986;59(3):669-75.
[51] Boyce-Jacino MT, O'Donoghue K, Faras AJ. Multiple complex families of endogenous retroviruses are highly conserved in the genus Gallus. J Virol. 1992;66(8):4919-29.
[52] Sacco MA, Flannery DM, Howes K, Venugopal K. Avian endogenous retrovirus EAV-HP shares regions of identity with avian leukosis virus subgroup J and the avian retrotransposon ART-CH. J Virol. 2000;74(3):1296-306.
[53] Bai J, Payne LN, Skinner MA. HPRS-103 (exogenous avian leukosis virus, subgroup J) has an env gene related to those of endogenous elements EAV-0 and E51 and an E element found previously only in sarcoma viruses. J Virol. 1995;69(2):779-84.
[54] Smith LM, Toye AA, Howes K, Bumstead N, Payne LN, Venugopal K. Novel endogenous retroviral sequences in the chicken genome closely related to HPRS-103 (subgroup J) avian leukosis virus. J Gen Virol. 1999;80 ( Pt 1):261-8.
[55] Adams SE, Rathjen PD, Stanway CA, Fulton SM, Malim MH, Wilson W, Ogden J, King L, Kingsman SM, Kingsman AJ. Complete nucleotide sequence of a mouse VL30 retro-element. Mol Cell Biol. 1988;8(8):2989-98.
[56] Benson SJ, Ruis BL, Fadly AM, Conklin KF. The unique envelope gene of the subgroup J avian leukosis virus derives from ev/J proviruses, a novel family of avian endogenous viruses. J Virol. 1998;72(12):10157-64.
[57] Ruis BL, Benson SJ, Conklin KF. Genome structure and expression of the ev/J family of avian endogenous viruses. J Virol. 1999;73(7):5345-55.
[58] Burch JB, Davis DL, Haas NB. Chicken repeat 1 elements contain a pol-like open reading frame and belong to the non-long terminal repeat class of retrotransposons. Proc Natl Acad Sci U S A. 1993;90(17):8199-203.
[59] Vandergon TL, Reitman M. Evolution of chicken repeat 1 (CR1) elements: evidence for ancient subfamilies and multiple progenitors. Mol Biol Evol. 1994;11(6):886-98.
[60] Silva R, Burch JB. Evidence that chicken CR1 elements represent a novel family of retroposons. Mol Cell Biol. 1989;9(8):3563-6.
[61] Olofsson B, Bernardi G. The distribution of CR1, and Alu-like family of interspersed repeats, in the chicken genome. Biochim Biophys Acta. 1983;740(3):339-41.
[62] Martin J, Herniou E, Cook J, Waugh O'Neill R, Tristem M. Human endogenous retrovirus type I-related viruses have an apparently widespread distribution within vertebrates. J Virol. 1997;71(1):437-43.
[63] Astrin SM, Buss EG, Haywards WS. Endogenous viral genes are non-essential in the chicken. Nature. 1979;282(5736):339-41.
[64] Gavora JS, Kuhnlein U, Crittenden LB, Spencer JL, Sabour MP. Endogenous viral genes: association with reduced egg production rate and egg size in White Leghorns. Poult Sci. 1991;70(3):618-23.
[65] Walchner M, Leib-M?sch C, Messer G, Germaier H, Plewig G, Kind P. Endogenous retroviral sequences in the pathogenesis of systemic autoimmune disease. Arch Dermatol. 1997;133(6):767-71.
[66] Sreekumar GP, Smyth JR Jr, Ambady S, Ponce de Leon FA. Analysis of the effect of endogenous viral genes in the Smyth line chicken model for autoimmune vitiligo. Am J Pathol. 2000;156(3):1099-107.
[67] Stoye JP, Coffin JM. The four classes of endogenous murine leukemia virus: structural relationships and potential for recombination. J Virol. 1987;61(9):2659-69.
[68] Chakrabarti R, Hofman FM, Pandey R, Mathes LE, Roy-Burman P. Recombination between feline exogenous and endogenous retroviral sequences generates tropism for cerebral endothelial cells. Am J Pathol. 1994;144(2):348-58.
[69] Payne LN, Howes K, Gillespie AM, Smith LM. Host range of Rous sarcoma virus pseudotype RSV(HPRS-103) in 12 avian species: support for a new avian retrovirus envelope subgroup, designated J. J Gen Virol. 1992;73 ( Pt 11):2995-7.
[70] Crittenden LB, Fadly AM. Responses of chickens lacking or expressing endogenous avian leukosis virus genes to infection with exogenous virus. Poult Sci. 1985;64(3):454-63.
[71] Frisby DP, Weiss RA, Roussel M, Stehelin D. The distribution of endogenous chicken retrovirus sequences in the DNA of galliform birds does not coincide with avian phylogenetic relationships. Cell. 1979;17(3):623-34.
[72] Resnick RM, Boyce-Jacino MT, Fu Q, Faras AJ. Phylogenetic distribution of the novel avian endogenous provirus family EAV-0. J Virol. 1990;64(10):4640-53.
[73] Garrett JE, Knutzon DS, Carroll D. Composite transposable elements in the Xenopus laevis genome. Mol Cell Biol. 1989;9(7):3018-27.
[74] Doolittle RF, Feng DF, Johnson MS, McClure MA. Origins and evolutionary relationships of retroviruses. Q Rev Biol. 1989;64(1):1-30.