Biopolym. Cell. 2001; 17(4):298-301.
Structure and Function of Biopolymers
Deletion of the fifth exon of bcr/abl gene by acute lymphoblastic leukosis with Ph'chromosome
1Telegeev G. D., 1Dybkov M. V., 1Dubrovska A. N., 1Maliuta S. S.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


Sequencing of 3–8 exons of bcr/abl hybrid gene detected of 5th exon excision (108 nucleotide) in patient with acute lymphoblastic leukosis with breakpoint in M-bcr. Possible role of such disturbance in development oh Ph' leukosis is discussed.


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