Biopolym. Cell. 2000; 16(1):40-45.
http://dx.doi.org/10.7124/bc.000554
Structure and Function of Biopolymers
Comparative study of troponin complex immunoreactivity at dilated and ischemic cardiomyopathies
1Sidorik L. L., 1Fedorkova O. M., 2Ryabenko D. V., 1Bobyk V. I., 3Danilova V. M., 3Tregubov V. S., 1Matsuka G. Kh.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
  2. National Scientific Center "M. D. Strazhesko Institute of Cardiology, MAS of Ukraine"
    5, Narodnogo Opolchennya Str., Kyiv, Ukraine, 03151
  3. Petr Bogach Institute of Physiology
    Taras Shevchenko National University of Kyiv
    2, Academika Glushkova Ave Str., Kyiv, Ukraine, 03187

Abstract

The features of the immune reactions against troponin complex isolated from human ventricular myocardium in sera of patients with dilated cardiomyopathy (DCM) and patients with cardiomegaly of ischemic origin (ICM) have been investigated. The results have shown that sera antibodies level against troponin complex antigenes were considerably higher in patients with DCM. The most pronounced immunogenisity of troponin complex isolated from DCM patient myocardium has been shown.
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