Biopolym. Cell. 1999; 15(6):481-486.
http://dx.doi.org/10.7124/bc.000542
Structure and Function of Biopolymers
Lysozyme interaction with liposomes: thermodynamics of binding
1Gorbenko G. P.
  1. Kharkiv National University
    4, Svobody Ave., Kharkiv, Ukraine, 61077

Abstract

Using the method of competitive analysis the interaction of lysozyme with liposomes composed of phosphatidyicholine and diphosphatidylglycerot has been studied. In terms of the lattice and continuum models of large ligand adsorption to membrane thermodynamic parameters for the protein-lipid complexes have been estimated. Lysozyme binding to liposomes containing more than 25 mot % of DPG has been found to be characterized by the positive cooperativity, originating, presumably, from the self-association of the bound protein.
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