Biopolym. Cell. 1999; 15(4):289-291.
Structure and Function of Biopolymers
The influence of low doses of radiation on the content of superoxide dismutase RNA in different tissues of mice
- Institute of Molecular Biology and Genetics, NAS of Ukraine
150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
The content of mRNA coding copper-zinc superoxide dismutase (CuZn-SOD) was studied in cells of different tissues of mice. With the help of DNA-RNA hybridization it was found that long effect of low doses of radiation causes the inhibition of CuZn-SOD transcription In spleen and testicle and stimulates the gene expression of this enzyme in liver and brain of irradiated animals. The question about possible participation of CuZn-SOD in rod lores istance of mammals cells is discussed.
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