Biopolym. Cell. 1998; 14(1):39-42.
Structure and Function of Biopolymers
Effect of 80S ribosomes on higher eukaryotic leucyl-tRNA synthetase activity at the first stage of tRNA aminoacylation
1Belyanskaya L. L., 1Turkovskaya H. V., 1Kovalenko M. I., 1El'skaya A. V.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680

Abstract

80S ribosomes stimulate activity of homologous leucyl-tRNA synthetase on the first stage of tRNA aminoacylation, namely for formation enzyme bound aminoacyl-adenylate. A possible mechanism and functional significance of the interaction between eukaryotic leucyl-tRNA synthetase and ribosomes are discussed.

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