Biopolym. Cell. 1998; 14(1):39-42.
Structure and Function of Biopolymers
Effect of 80S ribosomes on higher eukaryotic leucyl-tRNA synthetase activity at the first stage of tRNA aminoacylation
- Institute of Molecular Biology and Genetics, NAS of Ukraine
150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
Abstract
80S ribosomes stimulate activity of homologous leucyl-tRNA synthetase on the first stage of tRNA aminoacylation, namely for formation enzyme bound aminoacyl-adenylate. A possible mechanism and functional significance of the interaction between eukaryotic leucyl-tRNA synthetase and ribosomes are discussed.
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