Biopolym. Cell. 1995; 11(5):5-14.
Methylation and imprinting in mammalian embryogenesis
1Morozova L. M.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680

Abstract

The author discusses the role of DNA methylation in the processes of imprinting and differentiation in emboyos of early ontogenesis stages.

References

[1] Doerfler W. DNA methylation and gene activity. Annu Rev Biochem. 1983;52:93-124.
[2] Ehrlich M, Ehrlich KC. Effect of DNA methylation on the binding of vertebrate and plant proteins to DNA. DNA methylation: Mol biol, biol. signifieanes. Basel : Birkhauser, 1993. 572 p.
[3] Doerfler W. Ernst Klenk lecture, November 7, 1988. Patterns of DNA methylation in the mammalian genome. Biol Chem Hoppe Seyler. 1990;371(6):455-63.
[4] Lyon MF. Some milestones in the history of X-chromosome inactivation. Annu Rev Genet. 1992;26:16-28.
[5] Shemer R, Walsh A, Eisenberg S, Breslow JL, Razin A. Tissue-specific methylation patterns and expression of the human apolipoprotein AI gene. J Biol Chem. 1990;265(2):1010-5.
[6] Khodosova IA. Role of enzymatic DNA methylation in cell differentiation and carcinogenesis. Tsitologiia. 1985;27(3):259-67.
[7] Mazin AL. Genome loses all 5-methylcytosine a life span. How is this connected with accumulation of mutations during aging?. Mol Biol (Mosk). 1993;27(1):160-73.
[8] Mazin AL, Vaniushin BF. The loss of dinucleotides CpG from DNA. IV. Methylation and divergence of genes and pseudogenes of small nuclear RNA. Mol Biol (Mosk). 1987;21(4):1099-109.
[9] Surani MA, Allen ND, Barton SC, Fundele R, Howlett SK, Norris ML, Reik W. Developmental consequences of imprinting of parental chromosomes by DNA methylation. Philos Trans R Soc Lond B Biol Sci. 1990;326(1235):313-27.
[10] Doerfler W. DNA methylation--a regulatory signal in eukaryotic gene expression. J Gen Virol. 1981;57(Pt 1):1-20.
[11] Achwal CW, Ganguly P, Chandra HS. Estimation of the amount of 5-methylcytosine in Drosophila melanogaster DNA by amplified ELISA and photoacoustic spectroscopy. EMBO J. 1984;3(2):263-6.
[12] Taylor SM, Jones PA. Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA. J Mol Biol. 1982;162(3):679-92.
[13] Dyban AP, Sorokin AV. Comparison of the size of paternal and maternal homologous chromosomes during the first 2 cleavage divisions in mouse embryos. Ontogenez. 1983;14(3):238-46.
[14] Surani MA, Barton SC, Norris ML. Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature. 1984 Apr 5-11;308(5959):548-50.
[15] McGrath J, Solter D. Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell. 1984;37(1):179-83.
[16] Kaufman MH. Early mammalian development partenogenetic studies. London: Cambridge Univ. press., 1983. 259 p.
[17] Hagemann LJ, First NL. Embryonic cytoplasmic extracts rescue murine androgenones to the blastocyst stage. Development. 1992;114(4):997-1001.
[18] Fundele RH, Norris ML, Barton SC, Fehlau M, Howlett SK, Mills WE, Surani MA. Temporal and spatial selection against parthenogenetic cells during development of fetal chimeras. Development. 1990;108(1):203-11.
[19] Surani MA, Barton SC, Norris ML. Experimental reconstruction of mouse eggs and embryos: an analysis of mammalian development. Biol Reprod. 1987;36(1):1-16.
[20] Monk M, Boubelik M, Lehnert S. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development. 1987;99(3):371-82.
[21] Ward C, Bolden A, Nalin CM, Weissbach A. In vitro methylation of the 5'-flanking regions of the mouse beta-globin gene. J Biol Chem. 1987;262(23):11057-63.
[22] Kafri T, Ariel M, Brandeis M, Shemer R, Urven L, McCarrey J, Cedar H, Razin A. Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Genes Dev. 1992;6(5):705-14.
[23] Ariel M, Cedar H, McCarrey J. Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis. Nat Genet. 1994;7(1):59-63.
[24] Penkov LI, Platonov ES Effect of 5-azacytidine on gene expression in mouse embryos glyukozofosfatizomerazy preimplantation development. All-Union. meet. "Genetics of Development": Proc. Conf. Tashkent, 1990, Volume 1, Part. 2: 250-262.
[25] Holliday R. DNA methylation and epigenetic mechanisms. Cell Biophys. 1989;15(1-2):15-20.
[26] Boyes J, Bird A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell. 1991;64(6):1123-34.
[27] Aranda-Anzaldo A. On the regulation of DNA methylation by higher-order structure in the cell nucleus. Med Hypotheses. 1991;34(1):81-7.
[28] Szyf M. DNA methylation patterns: an additional level of information? Biochem Cell Biol. 1991;69(12):764-7.
[29] Riggs AD. DNA methylation and cell memory. Cell Biophys. 1989;15(1-2):1-13.
[30] Grant SG, Chapman VM. Mechanisms of X-chromosome regulation. Annu Rev Genet. 1988;22:199-233.
[31] Nesterova TB, Zakiian SM. X chromosome inactivation in mammals. Genetika. 1994;30(3):293-317.
[32] Lyon MF. X-chromosome inactivation as a system of gene dosage compensation to regulate gene expression. Prog Nucleic Acid Res Mol Biol. 1989;36:119-30.
[33] Kay GF, Penny GD, Patel D, Ashworth A, Brockdorff N, Rastan S. Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell. 1993;72(2):171-82.
[34] Brown CJ, Willard HF. The human X-inactivation centre is not required for maintenance of X-chromosome inactivation. Nature. 1994;368(6467):154-6.
[35] Ashworth A, Rastan S, Lovell-Badge R, Kay G. X-chromosome inactivation may explain the difference in viability of XO humans and mice. Nature. 1991;351(6325):406-8.
[36] Riggs AD, Pfeifer GP. X-chromosome inactivation and cell memory. Trends Genet. 1992;8(5):169-74.
[37] Hansen RS, Gartler SM. 5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island. Proc Natl Acad Sci U S A. 1990;87(11):4174-8.
[38] Lock LF, Takagi N, Martin GR. Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation. Cell. 1987;48(1):39-46.
[39] Bartlett MH, Adra CN, Park J, Chapman VM, McBurney MW. DNA methylation of two X chromosome genes in female somatic and embryonal carcinoma cells. Somat Cell Mol Genet. 1991;17(1):35-47.
[40] Baranov VS. Chromosome imprinting and interchromosomal interactions in early mammalian development. Usp Sovrem Biol. 1988; 105(3):393-405.
[41] Cattenach BM. Parental origin effects in mice. J Embryol Exp Morph. 1985; 97(Suppl):137-50.
[42] DeLoia JA, Solter D. A transgene insertional mutation at an imprinted locus in the mouse genome. Dev Suppl. 1990:73-9.
[43] Sapienza C, Paquette J, Tran TH, Peterson A. Epigenetic and genetic factors affect transgene methylation imprinting. Development. 1989;107(1):165-8.
[44] Reik W, Howlett SK, Surani MA. Imprinting by DNA methylation: from transgenes to endogenous gene sequences. Dev Suppl. 1990:99-106.
[45] Thomas BJ, Rothstein R. Sex, maps, and imprinting. Cell. 1991;64(1):1-3.
[46] Hall JG. Genomic imprinting: review and relevance to human diseases. Am J Hum Genet. 1990;46(5):857-73.
[47] Forejt J, Gregorová S. Genetic analysis of genomic imprinting: an Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus. Cell. 1992;70(3):443-50.
[48] Bartolomei MS. The search for imprinted genes. Nat Genet. 1994;6(3):220-1.
[49] Stöger R, Kubicka P, Liu CG, Kafri T, Razin A, Cedar H, Barlow DP. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell. 1993;73(1):61-71.
[50] Kitsberg D, Selig S, Brandeis M, Simon I, Keshet I, Driscoll DJ, Nicholls RD, Cedar H. Allele-specific replication timing of imprinted gene regions. Nature. 1993;364(6436):459-63.
[51] Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature. 1993;366(6453):362-5.
[52] Latham KE, Doherty AS, Scott CD, Schultz RM. Igf2r and Igf2 gene expression in androgenetic, gynogenetic, and parthenogenetic preimplantation mouse embryos: absence of regulation by genomic imprinting. Genes Dev. 1994;8(3):290-9.
[53] DeChiara TM, Robertson EJ, Efstratiadis A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell. 1991;64(4):849-59.
[54] Villar AJ, Pedersen RA. Parental imprinting of the Mas protooncogene in mouse. Nat Genet. 1994;8(4):373-9.