Biopolym. Cell. 1995; 11(2):52-56.
Study of chromosome-plasmidic determination of antibiotic-resistance in strains of Campylobacter genus
- Gromashevsky L.V. Institute of Epidemiology and Infection Diseases, AMS of Ukraine
5, Amosova Str., Kyiv, Ukraine, 03038
Abstract
Investigations on studying of chomosome-plasmidic determination characteristics of antibiotic-resistance in strains of Campylobacter isolated from different sources are presented. An analysis of antibioticogramms isolated Campylobacter strains has showed that 12 from them (31,6 %) possessed a great number of medical resistance. A plasmid presence of determinated antibiotic-resistance in 7 from 38 examined cultures (18,4 %) was set up. The treatment with ethidium bromide was being conducted to change of phenotypical properties of plasmid-containing strains. After elimination of plasmids (MW is approximately 40–70 MD) the strains resistance to tetracycline and erythromycine have been lost but a mowing of plasmids MM approximately 1,5–6 MD – kanamycine. Plasmid character of a great number of Campylobacter resistance can be editional criteria of epidemic strain's danger
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