The transient character of nonspecific genome\'s reaction under gamma irradiation in vivo tested by variation of rat DNA restriction pattern

Shugalii, A. V.; Lichina, M. V.

doi:10.7124/bc.0003C7

Biopolym. Cell. 1994; 10(6):79-82.

http://dx.doi.org/10.7124/bc.0003C7

The transient character of nonspecific genome's reaction under gamma irradiation in vivo tested by variation of rat DNA restriction pattern

1Shugalii A. V., 1Lichina M. V.

Institute of Chemical Physics, RAS in Chernogolovka
Academician Semenov avenue 1, Chernogolovka, Moscow region, Russian Federation, 142432

Abstract

At the considerable enzyme's abundance the accessibility some rat thymus DNA sites, for EcoRI-restriction varies depending on the interval after a single γ-irradiation in vivo. At a first hours for 5 Gy the sign-opposite effects for the fragments 1500 and 345 b. p. are occured-increasing and decreasing of the relative portions accordingly – with the returning to initial restriction level to 24-th hour. The doze 0,5 Gy causes a similar genome's reaction in terms of restriction accessibility, but the manifestation occured only in a day.

Full text: (PDF, in Russian)

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