Biopolym. Cell. 1994; 10(2):5-10.
http://dx.doi.org/10.7124/bc.00039B
Some new data concerning the mutagenic action of DNA
1Gershenson S. M., 1Alexandrov Yu. N.
  1. Institute of Plant Physiology and Genetics, NAS of Ukraine
    31/17, Vasylkivska, Kyiv, Ukraine, 03022

Abstract

It is shown that spermatozoa of Drosophila melanogaster can transfer molecules of exogenous DNA (or their fragments) from a solution of this DNA injected into the haemocel of an adult male into the ooplasm of the egg. As a result, mutations induced in the descendants arise both in the paternal and the maternal chromosomes obtained by them. The mutagenic effect of exogenous DNA has a prolonged character inducing mutations in the descendants during many cell generations after DNA-treatment of their father. The mechanism of such a prolongation of the mutagenic action of DNA is discussed.
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