Biopolym. Cell. 1985; 1(3):131-134.
Cell Biology
Phosphorylation of 3'-deoxy-3'-aminothymidine in the mouse myeloma p38ag653 cell culture and its incorporation into DNA
- Institute of Molecular Biology, Academy of Sciences of the USSR
Moscow, USSR
Abstract
The tritium-labelled 3'-deoxy-3'-aminothymidine, an inhibitor of DNA biosynthesis, was shown to penetrate into the mouse myeloma p38Ag653 cell culture. Later on it is phospho-rylated, triphosphorylated and incorporated into DNA, causing the termination of its elongation.
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