Changes of the erythrocyte membrane permeability for potassium under the influence of radiation

Authors

  • V. D. Krupin Kharkov State University 4, Sq. Dzerzhinsky, Kharkov, Ukraine, 310077 Author
  • G. P. Gorbenko Kharkov State University 4, Sq. Dzerzhinsky, Kharkov, Ukraine, 310077 Author
  • S. A. Kurilko Kharkov State University 4, Sq. Dzerzhinsky, Kharkov, Ukraine, 310077 Author
  • V. N. Tkachenko Kharkov State University 4, Sq. Dzerzhinsky, Kharkov, Ukraine, 310077 Author
  • V. V. Tovstyak Kharkov State University 4, Sq. Dzerzhinsky, Kharkov, Ukraine, 310077 Author

DOI:

https://doi.org/10.7124/bc.000397

Abstract

The effect of electrons with the energy 5 MeV on the erythrocyte membrane permeability for K+ has been investigated. Using free radical scavengers and SH-active reagents it was shown that radiation-induced release of intracellular potassium is related to the damage of protein sulfhydryl groups by hydroxyl radicals.

References

Sungurov AY. Radiobiology of cell surface. VINITI, 1988 (Ser Radiobiology; vol. 7), 178 p.

Polivoda BP, Konev VV, Popov GA. Biophysical aspects of radiation damage to biological membranes. Energoatomizdat, 1990; 160 p.

Chapman IV, Sturrock MG. The effects of x-irradiation in vitro on the transport of potassium ions in thymocytes. Int J Radiat Biol Relat Stud Phys Chem Med. 1972;22(1):1-9.

Myers DK, Bide RW. Biochemical effects of X-irradiation on erythrocytes. Radiat Res. JSTOR; 1966;27(2):250-63.

Shapiro B, Kollmann G. The nature of the membrane injury in irradiated human erythrocytes. Radiat Res. 1968;34(2):335-46.

Shapiro B, Kollmann G, Asnen J. Mechanism of the effect of ionizing radiation on sodium uptake by human erythrocytes. Radiat Res; 1966;27(1):139-58.

Gerasimova GK, Nakhil'nitskaya ZN. Role of sulfhydryl groups in the radiation damage of erythrocyte membrane transport function. The effect of ionizing radiation on cell membranes. M. : Atomizdat, 1973; 51-7.

Medvedev BI, Evtodienko IuV, Kuzin AM. Effect of ionizing radiation on the processes of ion transport in liver mitochondria. Radiobiologiia. 1976;16(5):756-9.

Bresciani F, Auricchio F, Fiore C. Effect OF X-rays on movements of sodium in human erythrocytes. Radiat Res. 1964;21:394-412.

Modifiability limits of radiation injury. Ed. PG Zherebchenko. M. : Atomizdat, 1978. 216 p.

Krupin VD, Kurilko SA, Tkachenko VN, Gorbenko GP, Tovstyak VV. Effect of the electrons on the K+ transport in erythrocytes. Biopolym Cell. 1993; 9(3):54-56.

Kudryashov YB, Berenfeld BS. Basics of Radiation Biophysics. M. : MGU, 1982. 304 p.

Fomenko BS, Akoev IG. Radiation damage of the plasma membrane and the lethal effect of radiation on cells. Usp Sovrem Biol. 1984; 97(1):146-58.

Chernitskiy EA, Vorobey AV. Structure and function of erythrocyte membranes. Minsk : Nauka i tekhnika, 1981; 316 p.

Published

1994-01-20

Issue

Section

Biopolymers and Cell