Aggregation of erythrocytes: a novel activity of HBD-2
DOI:
https://doi.org/10.7124/bc.000996Keywords:
β-defenins, dose-dependent, salt-sensitiveAbstract
Aim. To investigate an ability of HBD-2 to induce aggregation of erythrocytes. Methods. Aggregation assay, turbidimetry, light microscopy. Results. We have identified aggregation of erythrocytes in presence of at least 12.5 μM of HBD-2 that was confirmed by light microscopy. Effect was depended on HBD-2 concentration and diminished in presence of NaCl. Conclusions. HBD-2 can induce salt-sensitive aggregation of erythrocytes in dose-dependent manner.References
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