Specific transfer factor to Staphylococcus aureus antigens influences on the activation of calcum smooth muscle contraction

Authors

  • T. L. Davidovskaya Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author
  • N. S. Miroshnichenko Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author
  • N. P. Fadeyenko Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author
  • N. V. Davidovskaya Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author
  • L. S. Kholodnaya Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author
  • T. A. Lyubchenko Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author
  • O. G. Goleva Taras Shevchenko National University of Kyiv 64, Volodymyrska Str., Kyiv, Ukraine, 01033 Author

DOI:

https://doi.org/10.7124/bc.000537

Abstract

The influence of a transfer factor of cell-mediated immune response (TF) (10–6–10–3 mg/ml) on the guinea-pig taenia coli smooth muscle contraction was investigated under isometric conditions by tensometric method. It was found thai TF stimulated potential-dependent cell membrane Ca2+ reallocations, changed the cations transport system sensitivity in sarcoplasmic reticulum, inhibited contraction of pharmaco-mechanical coupling type by dose-dependent manner.

References

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Published

1999-09-20

Issue

Vol. 15 No. 5 (1999)

Section

Structure and Function of Biopolymers