The comparative analysis of Cu, Zn-superoxide dismutase activity of whole blood and its components

Authors

  • S. B. Arbuzova Donetsk Interregional Center of Medical Genetics, Ministry of Health of Ukraine 57, Artema Str, Donetsk, Ukraine, 340000 Author
  • O. O. Fedotova Donetsk Interregional Center of Medical Genetics, Ministry of Health of Ukraine 57, Artema Str, Donetsk, Ukraine, 340000 Author
  • V. D. Solovyova Donetsk Interregional Center of Medical Genetics, Ministry of Health of Ukraine 57, Artema Str, Donetsk, Ukraine, 340000 Author
  • A. V. Chugay Donetsk Interregional Center of Medical Genetics, Ministry of Health of Ukraine 57, Artema Str, Donetsk, Ukraine, 340000 Author

DOI:

https://doi.org/10.7124/bc.00051D

Abstract

The activity of Cu, Zn-SOD was studied in donors, of extra-chronwsome 21 and in the control group. The comparative analysis revealed the significant decrease of SOD activity in whole blood and its components. The different impact of components' SOD activity on the total effect of whole blood enzyme activity M.-J detected.

References

Fridovich I. Free radicals in biology. Translated from English. M., 1979, Volume 1, 318.

Gusev VA, Panchenko LF. Superoxide radical and superoxide dismutase in the free-radical theory of aging (a review) Vopr Med Khim. 1982;28(4):8-25.

Dubinina EE. Characteristics of extracellular superoxide dismutase. Vopr Med Khim. 1995;41(6):8-12

Arbuzova SB. Clinico-pathogenetic substantiation of the manifestation of the syndrome and trisomy 21 Avtoref. dis. ... dokt. med. nauk. K., 1996. 45 p.

Chevari S, Chaba I, Sekeĭ I. Role of superoxide dismutase in cellular oxidative processes and method of its determination in biological materials. Lab Delo. 1985;(11):678-81.

Harman D. Free radical theory of aging. Mutat. Res. 1992; 275:257—266.

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Published

1999-05-20

Issue

Vol. 15 No. 3 (1999)

Section

Structure and Function of Biopolymers