«Smart» hydrogel nanocomposites for biomedical applications

Abstract

Aim. Application of polymer composites based hydrogels filled by functionalized nanoparticles (acid-modified nanoclay laponite and gold nanoparticles) allows their use for early diagnosis of cancer and filling postoperative cavities, especially after tumor resection. Conclusions. Acid modification of Lap can serve as a basis for the development of the nanocomposite hydrogel diagnostic systems. The synthesized hybrid polymeric materials based on porous polyvinylformal, acrylic hydrogels and gold nanoparticles can be used to fill postoperative cavities with simultaneous targeted release of the incorporated Doxorubicin and Albucide.