Adaptor protein CIN85 promotes collagen adhesion and invasion of osteosarcoma cells

Authors

  • I. R. Horak Masaryk University 753/5, Kamenice, Brno, Czech Republic, 62500; O. V. Palladin Institute of Biochemistry, NAS of Ukraine 9, Leontovycha Str., Kyiv, Ukraine, 01054 Author
  • L. B. Drobot O. V. Palladin Institute of Biochemistry, NAS of Ukraine 9, Leontovycha Str., Kyiv, Ukraine, 01054 Author
  • L. Knopfova Masaryk University 753/5, Kamenice, Brno, Czech Republic, 62500 Author

DOI:

https://doi.org/10.7124/bc.000AD5

Keywords:

osteosarcoma, CIN85, invasion, adhesion, collagen

Abstract

Aim. This study is aimed at investigation of the CIN85 effect on osteosarcoma (OS) cells collagen adhesion and invasion. Conclusions. Our results demonstrate that increased CIN85 expression in osteosarcoma cells is associated with elevated collagen adhesion and invasion and may thereby contribute to metastasis.
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Published

2024-09-10

Issue

Vol. 40 No. 3 (2024)

Section

Chronicle and Information