Effect of gold and silver nanoparticles on the enterocytes cell death in mice

Authors

  • A. P. Lytvynenko O. O. Bogomoletz Institute of Physiology, National Academy of Sciences 4, Akademika Bohomoltsia Str., Kyiv, Ukraine, 01024 Author
  • O. M. Kaleynikova O. O. Bogomoletz Institute of Physiology, National Academy of Sciences 4, Akademika Bohomoltsia Str., Kyiv, Ukraine, 01024 Author
  • T. Yu. Voznesenska O. O. Bogomoletz Institute of Physiology, National Academy of Sciences 4, Akademika Bohomoltsia Str., Kyiv, Ukraine, 01024 Author

DOI:

https://doi.org/10.7124/bc.000ACC

Keywords:

enterocytes, cell death, anoikis, gold and silver nanoparticles

Abstract

Aim. To assess the effect of five times treatment with gold and silver nanoparticles on the enterocytes cell death of the iliac section of the small intestine in mice. Conclusions. It was found, that the treatment with both gold and silver nanoparticles results in increase of death of enterocytes of the ileum of the small intestine in mice. Therefore, further research is needed to clarify the dose, frequency and method of treatment with such nanosystems.

References

Kutsevol N, Bezugla T, Bezuglyi M, Rawiso M. Branched Dextran-graft-Polyacrylamide Copolymers as Perspective Materials for Nanotechnology. Macromolecular Symposia. 2012; 317-8(1):82-90.

Kimura Y, van der Merwe M, Bering SB, Penmatsa H, Conoley VG, Sangild PT, Naren AP, Buddington RK. Glucose transport by epithelia prepared from harvested enterocytes. Cytotechnology. 2015;67(1):39-9.

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Published

2024-09-10

Issue

Vol. 40 No. 3 (2024)

Section

Chronicle and Information