Biopolym. Cell. 1989; 5(1):27-31.
http://dx.doi.org/10.7124/bc.00003B
Structure and Function of Biopolymers
Microcalorimetric studies in hydration of Poly(dA)-Poly(dT) and Poly(dG)-Poly(dC) polynucleotides
1Mrevlishvili G. M., 2Sokhadze V. M., 2Japaridze G. Sh., 2Tatishvili D. A., 1, 2Yakobashvili N. E.
  1. Department of Macromolecular Physics, State University of Tbilisi
    Tbilisi, USSR
  2. Institute of Physics, Academy of Sciences of the Georgian SSR
    Tbilisi, USSR

Abstract

The calorimetric data show: 1) poly (dA) •poly (dT) hydration is nat = 27.0 ± l M H2O/MBP at all values of relative humidity (RH); 2) poly (dG) • poly (dC) hydration at high values of RH is nGC = 16.0 ± 1 MH2O/MBP; 3) thermodynamic parameters of ice-water phasetransition in poly(dQ) poly (dC) solutions and gels are abruptly changed with a decrease of the total water content (in the RH range of 90–60 %; 4) poly(dG) • poly(dC) hyd-ration at low RH is /toe = 12.0 ± 1MH2O/MBP; 5) the observed hydration change of poly (dG) poly (dC) (by 4±1MH2O/MBP) points to the conformational transition of this polymer within the limits of double-stranded state during the dehydration.
Full text: (PDF, in Russian)

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