Biopolym. Cell. 2007; 23(3):172-187.
Mutagenesis induced by integration processes and evolution of nuclear genome
1Lukash L. L.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


Mutational variability induced by large-scale reorganizations of genetic material such as MGE transpositions, integration or disintegration of exogenous nucleotide sequences of viral and non-viral origin, changes in chromosome set or individual chromosomes, chromatin diminution and its role in the evolution of nuclear genome are discussed.
Keywords: mutagenesis, evolution, nuclear genome, heterochromatin, mobile genetic elements, chromosome, chromatin diminution


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