Biopolym. Cell. 2004; 20(4):325-330.
Molecular and Cell Biotechnologies
Expression of extracellular human prolactin in insect cells
1Strokovskaya L. I., 1Kikhno I. M., 1Meleshko R. A., 1Solomko A. P.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


Human prolactin was expressed in the insect culture cells as a soluble extracellular protein using recombinant baculoviruses. The yield varied between 20-30 mg/l medium. This recombinant prolactin was biologically active in the Nb2 rat lymphoma cells proliferation assay.


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