Biopolym. Cell. 1999; 15(6):493-495.
http://dx.doi.org/10.7124/bc.000544
Cell Biology
The active oxygen forms production and aggregation of human blood neutrophils under the action of recombinant interleukin-1β
1Semenkova G. N., 1Kovalenko E. I., 2Murzenok P. P., 1Cherenkevich S. N.
  1. Belarusian State University
    4, Fr. Scorina Minsk ave., Belarus, 220050
  2. Institute of Physiology, NAS of Belarus
    28, Academic Str, Minsk, Republic of Belarus, 220072

Abstract

The influence of recombinant inierleukin-lβ (rlL-1β) on human blood neutrophils aggregation has been studied. The sharp increase of the rate of spontaneous cell's aggregation under the rlL-1β influence has been established. The observed effect depends on rlL-1β concentration. It has been found that the process of rlL-1β induced aggregation of neutrophils is coupled with the process of active oxygen forms generation by the enzyme systems localized on the plasma membrane surface.
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