Biopolym. Cell. 1999; 15(5):402-408.
http://dx.doi.org/10.7124/bc.000537
Structure and Function of Biopolymers
Specific transfer factor to Staphylococcus aureus antigens influences on the activation of calcum smooth muscle contraction
1Davidovskaya T. L., 1Miroshnichenko N. S., 1Fadeyenko N. P., 1Davidovskaya N. V., 1Kholodnaya L. S., 1Lyubchenko T. A., 1Goleva O. G.
  1. Taras Shevchenko National University of Kyiv
    64, Volodymyrska Str., Kyiv, Ukraine, 01033

Abstract

The influence of a transfer factor of cell-mediated immune response (TF) (10–6–10–3 mg/ml) on the guinea-pig taenia coli smooth muscle contraction was investigated under isometric conditions by tensometric method. It was found thai TF stimulated potential-dependent cell membrane Ca2+ reallocations, changed the cations transport system sensitivity in sarcoplasmic reticulum, inhibited contraction of pharmaco-mechanical coupling type by dose-dependent manner.
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