Biopolym. Cell. 1997; 13(2):108-112.
http://dx.doi.org/10.7124/bc.000470
Structure and Function of Biopolymers
A change of conformation properties of cellular phospholipids effected by molecule of pyrazole
1Nasibullin R. S., 1Serebrenik M. A.
  1. Bashkir State Medical University
    3, Lenin Str., Ufa, Bashkortostan, Russian Federation, 450000

Abstract

A change of conformation properties of phosphatidylcholine under the formation of its complexes with pyrazole due to hydrogen binding P-O ... N-H (type I complex), and the interconnection of π-pyrazole molecule system with a polar hea of phosphatidylcholine (type II complex) have been studied by means of quantum chemistry methods. The development of type I complex has been shown to lead to conformation changes of phospholipid involving a gauche-conformation as a more preferable for phosphorilcholine part of phospholipid.
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References

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