Biopolym. Cell. 1985; 1(3):131-134.
Phosphorylation of 3'-deoxy-3'-aminothymidine in the mouse myeloma p38ag653 cell culture and its incorporation into DNA
- Institute of Molecular Biology, Academy of Sciences of the USSR
The tritium-labelled 3'-deoxy-3'-aminothymidine, an inhibitor of DNA biosynthesis, was shown to penetrate into the mouse myeloma p38Ag653 cell culture. Later on it is phospho-rylated, triphosphorylated and incorporated into DNA, causing the termination of its elongation.
 Suhadolnik RJ. Naturally occurring nucleoside and nucleotide antibiotics. Prog Nucleic Acid Res Mol Biol. 1979;22:193-291.
 Lin TS, Prusoff WH. Synthesis and biological activity of several amino analogues of thymidine. J Med Chem. 1978;21(1):109-12.
 Krenitsky TA, Freeman GA, Shaver SR, Beacham LM 3rd, Hurlbert S, Cohn NK, Elwell LP, Selway JW. 3'-Amino-2',3'-dideoxyribonucleosides of some pyrimidines: synthesis and biological activities. J Med Chem. 1983;26(6):891-5.
 Lin TS, Mancini WR. Synthesis and antineoplastic activity of 3'-azido and 3'-amino analogues of pyrimidine deoxyribonucleoside. J Med Chem. 1983;26(4):544-8.
 Kukhanova MK, Kochetkova SV, Kraevskii AA, Terent'ev LL, Rasskazov VA. Inhibition of DNA biosynthesis in sea urchin embryos by 2',3'-dideoxy-3'-aminonucleosides. Biokhimiia. 1983;48(10):1747-51.
 Chidgeavadze ZG, Beabealashvilli RS, Atrazhev AM, Kukhanova MK, Azhayev AV, Krayevsky AA. 2',3'-Dideoxy-3' aminonucleoside 5'-triphosphates are the terminators of DNA synthesis catalyzed by DNA polymerases. Nucleic Acids Res. 1984;12(3):1671-86.
 Kukhanova M. K., Kraevsky A. A., Terentieva N. A., Rasskazov V. A. Inhibition of replicative DNA synthesis in nuclei of sea urchin (Strongylocentrotus intermwium) embryo by 2', 3'-dideoxy-3'-aminonucleoside 5'-triphosphates. Biopolym. Cell. 1985; 1(2):79-86.
 Kraevsky A. A., Kukhanoua M. K., Alexandrova L. A., Belyakova N. V., Krutyakov V. M.2',3'-dideoxy-3'-aminonucleoside-5'-triphosphates inhibit repair DNA synthesis in rat liver chromatin. Biopolym. Cell. 1985; 1(3):125-131.
 Zaitseva V. E., Dyatkina N. B., Krayevsky A. A., Skaptsova N. V., Turina O. V., Gnuchev N. V., Gottikh B. P., Azhayev A. V. Aminonucleosides and their derivatives. XI. Synthesis of 3'-amino-2',3'-dideoxynucleoside 5'-triphosphates. Russian Journal of Bioorganic Chemistry. 198;, 10(5):670-80.
 Zaitseva V. E., Skaptsova N. V., Azhayev A. V., Krayevsky A. A. Aminonucleosides and their derivatives. X. 2'-Deoxydinucleoside phosphates and 2'-deoxydinucleotides with phosphoamide bonds. Russian Journal of Bioorganic Chemistry. 1984; 10(3):401-7.
 Byars N, Kidson C. DNA chain termination by 2',3'-dideoxythymidine in replicating mammalian cells. Biochemistry. 1975;14(14):3159-64.
 Graham FL, Whitmore GF. The effect of-beta-D-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cells. Cancer Res. 1970;30(11):2627-35.
 Cozzarelli NR. The mechanism of action of inhibitors of DNA synthesis. Annu Rev Biochem. 1977;46:641-68.