Biopolym. Cell. 1985; 1(3):131-134.
Cell Biology
Phosphorylation of 3'-deoxy-3'-aminothymidine in the mouse myeloma p38ag653 cell culture and its incorporation into DNA
1Kochetkova S. V., 1Kukhanova M. K., 1Krayevsky A. A.
  1. Institute of Molecular Biology, Academy of Sciences of the USSR
    Moscow, USSR


The tritium-labelled 3'-deoxy-3'-aminothymidine, an inhibitor of DNA biosynthesis, was shown to penetrate into the mouse myeloma p38Ag653 cell culture. Later on it is phospho-rylated, triphosphorylated and incorporated into DNA, causing the termination of its elongation.


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