Biopolym. Cell. 1985; 1(3):125-131.
Cell Biology
2',3'-dideoxy-3'-aminonucleoside-5'-triphosphates inhibit repair DNA synthesis in rat liver chromatin
1Kraevsky A. A., 1Kukhanova M. K., 1Alexandrova L. A., 2Belyakova N. V., 2Krutyakov V. M.
  1. Institute of Molecular Biology, Academy of Sciences of the USSR
    Moscow, USSR
  2. B. P. Konstantinov Institute of Nuclear Physics, Academy of Sciences of the USSR
    Gatchina, Leningrad distr., USSR


2',3-dideoxy-3'-aminonucleoside-5'-triphosphates are shown to be strong inhibitors of repair DNA synthesis in γ-irradiated rat liver chromatin. The activity of these compounds is comparable with that of the most effective inhibitors of the DNA-polymerase p-cataly-zed repair DNA synthesis


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