Biopolym. Cell. 2011; 27(3):167-180.
Обзоры
Бакуловирусные векторы в экспериментальной гено- и вакцинотерапии
1Соломко А. П., 1Захарук Е. А., 1Чащина Л. И., 1Строковская Л. И.
  1. Институт молекулярной биологии и генетики НАН Украины
    ул. Академика Заболотного, 150, Киев, Украина, 03680

Abstract

Представлен краткий обзор данных литературы по целевому конструированию и исследованию свойств и эффективности применения в модельных системах in vivo рекомбинантных бакуловирусов. Проанализированы результаты экспериментов с использованием диких и рекомбинантных бакуловирусов в таких приоритетных областях биомедицины, как регенерация тканей, генотерапия рака, разработка вакцин против инфекционных заболеваний и злокачественных новообразований.
Keywords: бакуловирус, геновектор, иммуновектор, млекопитающие, система in vivo

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