Biopolym. Cell. 2003; 19(1):89-92.
Molecular Biomedicine
Trophinotropin «Cerebral» — endogenous neuroimmunoprotector and γ-interferon inducer
1Makarenko A. N., 2Rybalko S. L.
  1. Institute of Pharmacology and Toxicology of National Medical Academy of Science of Ukraine
    14, Eugene Pottier Str., Kyiv, Ukraine, 03057
  2. Gromashevsky L.V. Institute of Epidemiology and Infection Diseases, AMS of Ukraine
    5, Amosova Str., Kyiv, Ukraine, 03038

Abstract

Interferon-inducing activity of «Cerebral», endogenous trophinotropin agent, controlling growth factors of CNS, has been evaluated in human blood leukocytes. «Cerebral» has been shown to induce γ-interferon at a titer of 160–320 IU/ml. Interferon-inducing activity of «Cerebral» may contribute to the correction mechanisms of immune disorders in patients with acute hemorrhagic stroke.

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