Biopolym. Cell. 1999; 15(2):143-148.
Структура и функции биополимеров
Структурно-функциональные особенности нейроспецифических адгезивных белков иммуноглобулинового семейства
1Жерносеков Д. Д.
  1. Днепропетровский национальный университет им. Олеся Гончара
    пр. Гагарина, 72, Днепропетровск, Украина, 49050

Abstract

Адгезивные молекулы иммуноглобулинового семейства (lg семейства) представляют собой обширную группу белков, обеспечивающих клеточное взаимодействие в периоды морфогенеза и синаптогенеза нервной ткани К настоящему времени накоплен значительный опыт в изучении структуры и функций нейроспецифических адгезивных молекул В обзоре приведены основные принципы, используемые для классификации белков данного семейства, обсуждено применение молекулярно-генетического подхода для исследования адгезивных белков, показана общность доменной организации у белков адгезии Ig семейства, выделенных из нервной ткани животных организмов, имеющих глубокие различия в эволюционном плане. Рассматривается, каким образом структурные особенности адгезивных белков изучаемого семейства могут аьособствовать выпол­нению их специфических функций в нервной ткани.

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