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Genome and Its Regulation
The nucleotide sequences probably connected with the initiation sites of DNA replication in Drosophila melanogasier
1, 2Sidorenko A. P., 1Khudoly G. A., 1Schuppe N. G.
  1. N. I. Vavilov Institute of General Genetics, Academy of Sciences of the USSR
    Moscow, USSR
  2. Institute of Chemical Physics, Academy of Sciences of the USSR
    Moscow, USSR


The DNA fraction enriched in replication initiation sites was isolated from cultured embryonic cells of Drosophila melanogaster using a method of nascent DNA strands extrusion. Hybridization experiments have shown that at least a part of replication initiation sites are repetitive sequences and are highly conservative in evolution.


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