Biopolym. Cell. 1988; 4(4):220-222.
Short Communications
Synthesis of arginine-containing oligonucleotide-(5'→N)-peptides
- Institute of Bioorganic Chemistry, Siberian Branch of the Academy of Sciences of the USSR
Novosibirsk, USSR - Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
Kiev, USSR
Abstract
A new method for synthesis of oligonucleotide-peptides of phosphoamide type with the use of a mixture of triphenylphosphine, dipyridyldisulphide and N-methylimidazole is suggested. This approach was applied for synthesizing and isolating d(CCCC)-5'-P-Pro-Arg-Val-OMe.
Full text: (PDF, in Russian)
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