Репліконна організація геному вищих організмів: критичний розбір фактів і гіпотеза
DOI:
https://doi.org/10.7124/bc.000187Анотація
Дано критичний аналіз методів визначення розмірів репліконов на радіоавтографах молекул ДНК. Показано неспроможність концепції «кластерів дрібних (30–50 мкм) репліконів». Обгрунтовано існування великих (100–200 мкм і довших) репліконов. Запропоновано модель організації реплікації хромосом вищих організмівПосилання
Zakharov AF, Benyush VA, Kuleshov NP, Baranovska LI. Human Chromosomes: Atlas. M.: Medical, 1982. 261.
Yunis JJ, Tsai MY. Mapping of polysomal messenger RNA and heterogeneous nuclear RNA to the lightly staining G-bands of human chromosomes. Cytogenet Cell Genet. 1978;22(1-6):364-7.
Batuev AS, Orlov AA, Pirogov AA. Participation of primate frontal cortex in organizing short-term memory processes. Dokl Akad Nauk SSSR. 1979;247(4):997-1000.
Ono T, Okada S. DNAase I digestion of early, middle, and late S phase replicating DNA in murine leukemia L5178Y cells. Biochim Biophys Acta. 1981;655(1):113-6.
Goldman MA, Holmquist GP, Gray MC, Caston LA, Nag A. Replication timing of genes and middle repetitive sequences. Science. 1984;224(4650):686-92.
Bak AL, Jorgensen AL, Zeuthen J. Chromosome banding and compaction. Hum Genet. 1981;57(2):199-202.
Zakharov AF, Egolina NA. Correlation between pattern of DNA replication and chromosome banding. Biol Zbl. 1976; 95:327-334.
Cairns J. Autoradiography of HeLa cell DNA. J Mol Biol. 1966;15(1):372-3.
Huberman JA, Riggs AD. On the mechanism of DNA replication in mammalian chromosomes. J Mol Biol. 1968;32(2):327-41.
Callan HG. Replication of DNA in the chromosomes of eukaryotes. Proc R Soc Lond B Biol Sci. 1972;181(62):19-41.
Edenberg HJ, Huberman JA. Eukaryotic chromosome replication. Annu Rev Genet. 1975;9:245-84.
Hand R. Eucaryotic DNA: organization of the genome for replication. Cell. 1978;15(2):317-25.
Ananiev EV, Polukarova LG, Yurov YB. Replication of chromosomal DNA in diploid Drosophila melanogaster cells cultured in vitro. Chromosoma. 1977;59(3):259-72.
Iurov IuB, Liapunova NA. Rate of DNA replication and size of replicons in human diploid cells. Mol Biol (Mosk). 1976;10(5):1085-93.
Wilson BG. DNA replication in the amphibia. Chromosoma. 1975;51(3):213-24.
Yurov YB. Do clusters of replication units in the mammalian cells exist? Exp Cell Res. 1979;123(2):369-74.
Callan HG. DNA replication in the chromosomes of eukaryotes. In: Molecular Cytogenetics . Eds B. A. Hamkalo, J. Papaconstantinou. New York: Plenum publ. corp., 1973; p. 31-47.
Yurov YB, Liapunova NA. The units of DNA replication in the mammalian chromosomes: evidence for a large size of replication units. Chromosoma. 1977;60(3):253-67.
Housman D, Huberman JA. Changes in the rate of DNA replication fork movement during S phase in mammalian cells. J Mol Biol. 1975;94(2):173-81.
Khaitova NM, Il'ina GS, Liapunova NA. Organization of mammalian genome replication: data on the high rate of DNA replication in replicons of structural heterochromatin. Tsitologiia. 1980;22(6):640-5.
Kapp LN, Painter RB. Multiple thymidine incorporation peaks in the S phase of synchronous human diploid fibroblasts. Exp Cell Res. 1977;107(2):428-31.
Kapp LN, Painter RB. X-ray inhibition of DNA synthesis at discrete times during S phase in synchronous human diploid fibroblasts. Radiat Res. 1982;89(2):424-7.
Lyapunov NA, Lavrushina OM, Dulatova ShN. Using bleomycin to demonstrate clustering acts in DNA replication initiation in the S-phase of the mitotic cycle in cultured human cells. In the book.: VIII Proc. symposium. "Structure and function of the cell nucleus": Proc. of reports. Pushchino, 1984, p. 269-270.
Wille JJ Jr, Kauffman SA. Premature replication of late S period DNA regions in early S nuclei transferred to late S cytoplasm by fusion in Physarum polycephalum. Biochim Biophys Acta. 1975;407(2):158-73.
Epifanova OI. Study the regulatory mechanisms of the mitotic cycle with inhibitors of translation and transcription. In book.: Cell Cycle. Nauka, Moscow, 1973, p. 72-103.