Does non-empirical quantum chemistry allow understanding nature of purine-purine mismatches formation by high fidelity DNA polymerases?
DOI:
https://doi.org/10.7124/bc.000763Keywords:
replication DNA polymerase, purine-purine mismatches of DNA biosynthesis, non-empirical quantum chemistryAbstract
Based on ab initio quantum chemical calculations at the MP2/6–311++G(d,p)//B3LYP/6–31G(d,p) level of theory, we suggest a new approach, explaining molecular mechanisms of purine-purine mismatches formation by high fidelity DNA polymerases.References
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