Effect of cell culture of Polyscias filicifollia bailey biomass on the activity of tRNA and aminoacyl-tRNA synthetase from the rabbit liver

Authors

  • R. Yu. Slavinskene Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR Kiev, USSR; Medical Institute Kaunas Kaunas, USSR Author
  • L. Yu. Lukosevicius Medical Institute Kaunas Kaunas, USSR Author
  • V. A. Kunakh Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR Kiev, USSR Author
  • L. I. Slepyan Chemopharmaceutic Institute Leningrad, USSR Author
  • M. I. Kovalenko Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR Kiev, USSR Author
  • L. L. Ivanov Medical Institute Kaunas Kaunas, USSR Author

DOI:

https://doi.org/10.7124/bc.0001AD

Abstract

The activity of tRNA and aminoacyl-tRNA synthetase from the rabbit liver is studied 6 hs after experimental myocardial infarction under the per os administration of the cell culture of Polyscias filicifolia Bailey biomass to the animals before operation. The level of aminoacylation of tRNA with leucine and the leucyl-tRNA synthetase activity in the total enzyme preparation increase in comparison with the preparations from untreated animals. The administration of P. filicifolia Baily to control (unoperated) rabbits has no effect on the tRNA acceptor activity while leucyl-tRNA synthetase activity slightly increases.

References

Lukoshiavichius LIu, Rodovichius GA, Kovalenko MM, Pivoriunaĭte II, Prashkiavichius AK. tRNA and aminoacyl-tRNA synthetases from the liver of rabbits in experimental myocardial infarction. Vopr Med Khim. 1983;29(4):65-9.

Slepyan LI, Mikhaylova NV, Kublashvili TsG. Structure roots Polyscias filicifolia Bailey. Rastitel'nyye resursy. 1978; 14:100-106

Toleikis A, Dzeja P, Praskevicius A, Jasaitis A. Mitochondrial functions in ischemic myocardium. I. Proton electrochemical gradient, inner membrane permeability, calcium transport and oxidative phosphorylation in isolated mitochondria. J Mol Cell Cardiol. 1979;11(1):57-76.

Demidov SV, Kovalenko MI, El'skaia AV. Biological activity of hepatic transfer RNA of rabbits of different ages. Nauchnye Doki Vyss Shkoly Biol Nauki. 1980;(12):18-24.

Published

1986-05-20

Issue

Section

Short Communications