Vitamin D3 and 1,25-dihydroxyvitamin D3 –inhibitors of 5-lipoxygenase
DOI:
https://doi.org/10.7124/bc.000340Abstract
The influence of vitamin D3 and 1,25-(OH)2D3 on the activity of potato 5-lipoxygienase and soy beans 15-lipoxygenase was examined. The inhibitory effect of these compounds on 5-lipoxygenase was established but not 15-lipoxygenase. 1,25-(OH)2D3 was stronger as an inhibitor then vitamin D3. Inhibitory effect of both compounds depended on dose of substrate (linoleic acid).References
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