Statistical significance of the occurrence of some complex nucleotide combinations: comparison of the DNA models
DOI:
https://doi.org/10.7124/bc.0000D0Abstract
A scheme for modeling of the DNA chain as a sequence of the nucleotide runs of different length is presented. The advantages of such a method and range of its application are discussed. A procedure is suggested to estimate statistical significance of occurrence of some complex sequence structures in DNA by the Monte-Carlo method. It uses a bootstrap algorithm and necessitates comparatively small number of calculations. Three different models, used to derive such estimations of the frequencies of homopurine-homopyrimidine mirror repeats in the DNA of phage K and rodentia noncoding regions are compared.References
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