Buckle of the A-T pair in the Bh-form of poly(dA):poly(dT)
DOI:
https://doi.org/10.7124/bc.000038Abstract
The structures of calcium and sodium salts of poly(dA): poly(dT) have been refined on the basis of X-ray diffraction in fibres using two parameter flexible sugar, and allowing for the possible A-T buckle. The bases of one chain, probably thymines, are tilted in the Na-poly(dA):poly(dT) structure at an angle of about —13°, while the tilt of the other chain bases is negligible. A number of unique features warrant a special designation, Bh, to distinguish poly(dA) : poly(dT) structure from other B-type structures. The refined structural parameters may be significant for the interpretation of data on DNA bends containing sufficiently long dAn:dTn tracts.References
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