Peptides and cyanine dyes. 2. Covalent labelling of amino acids and peptides by means of the reaction of pyrylium cyanine dyes with amines
DOI:
https://doi.org/10.7124/bc.0005A1Abstract
Here we propose a new amino-reactive pyrilium dye for the conjugation with peptides through N-terminal and N-ε-lysine's aminogroups. The reactivity of Cyan 39 towards eleven most interesting aminoacids has been investigated in triethylammonium acetate and sodium carbonate-bicarbonate buffers. The conjugation with 72-aminoacid model peptide has been carried out successfully.References
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