Biopolym. Cell. 2004; 20(5):443-446.
Short Communications
Comparison of genetic variability in BALB/c and C57Bl/6j mouse lines from diverse populations
1Vagyna I. N., 1Morozova L. M., 2Kovaleva O. A., 2Glazko T. T.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
  2. Institute of Agroecology of NAAS
    12 Metrologichna Str., Kyiv, Ukraine, 03680

Abstract

Genetic variability in mouse lines BALB/c and C57Bl/6j from «old» and «new» populations has been studied. A cytogenetic analysis has shown that mice from the both lines of «new» population differ from those of «old» population by a higher frequency of cytogenetic anomalies in bone marrow and blood cells.

References

[1] Blandova ZhK, Dushkin VA, Malashenko AM, Shmidt YeF. Lines of laboratory animals for biomedical research. Moscow, Nauka, 1983; 192 p.
[2] Fedorov VK, Yeremeyev NS, Ivonin AA. On the establishment and preservation of linear features in animals. Biology labs. animals. Moscow, Nauka, 1971.
[3] Mikhaylova TN, Zinger TV, Shubina TS. Features some standard indicators of linear mice. Using lab. animals in the development, manufacture and control of biol. med. preparations. Moscow, 1976; 208-10.
[4] Bailey D.W. Rates of subline divergence in highly inbred strains of mice. Journal of Heredity, 1959; 50 (1):26-30.
[5] Shmidt EF, Butsolich E, Nadudvari I, Semin GV. Divergence inbred lines and nonlinear laborat's animals. Biol. characterization labs. animals extrapolation to human experimental data. Moscow, 1980; 108-10.
[6] Hogan B, Constantini F, Lacy E. Manipulating the mouse embryo. A laboratory manual. New York : Cold Spring Harbor Lab., 1986; 350 p.
[7] Whittingham D.G. Culture of mouse ova. J Reprod Fertil. 1971; Suppl, 14:7-21.
[8] Lawitts JA, Biggers JD. Optimization of mouse embryo culture media using simplex methods. J Reprod Fertil. 1991;91(2):543-56.
[9] Lawitts JA, Biggers JD. Joint effects of sodium chloride, glutamine, and glucose in mouse preimplantation embryo culture media. Mol Reprod Dev. 1992;31(3):189-94.
[10] Orlov VH, Chudinovskaya GA, Kryukova YeP. Study mammalian chromosome sets. Moscow, Nauka, 1976; 36 p.
[11] Plokhinskiy NA. Biometric methods in genetic research. Moscow: Moscow State University Press, 1966. 601 p.
[12] Lakin GF. Biometrics. Moscow, Higher school, 1990. 352 p.
[13] Evsikov VI. Genetic and phenogenetical basis of mammalian fertility regulation: Author. Thesis ... Dr. biol. nauk. Novosibirsk, 1974. 44 p.
[14] Evsikov VI, Gerlinskaia LA, Moshkin MP, Osetrova TD, Potapov MA. Genetic-physiologic mother-fetus relationships and their effect on the adaptive traits of the offspring. Ontogenez. 1998;29(6):405-17.
[15] Smith R, McLaren A. Factors affecting the time of formation of the mouse blastocoele. J Embryol Exp Morphol. 1977;41:79-92.
[16] Korogodina IuV, Lil'p IG. Mutability of the somatic cells of mice of different strains. Tsitol Genet. 1978;12(2):134-6.
[17] Glazko TT, Safonova NA, Buntova EG, Glazko GV, Sozinov AA. The heterogeneity of the cytogenetic variability in the bone marrow cells of laboratory and wild rodents in the exclusion zone of the Chernobyl Atomic Electric Power Station. Tsitol Genet. 1996;30(4):25-34.
[18] Sato S, Takizawa H, Inui N. Mouse strain differences in induction of micronuclei by base analogues and nucleosides. Mutat Res. 1993;301(1):45-9.
[19] Okayasu R, Suetomi K, Yu Y, Silver A, Bedford JS, Cox R, Ullrich RL. A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse. Cancer Res. 2000;60(16):4342-5.