Biopolymers and cell. 2006; 22 (6): 458 - 467

Physical factors of stability of triple helical collagen structures

O. P. Boryskina, T. V. Bolbukh, M. A. Semenov, V. Ya. Maleev

In the present study a complex approach of a number of experimental techniques, namely, infrared spectroscopy, quartz piezogravimetry, and differential scanning calorimetry, was used to estimate the hydration energy and enthalpy of interpeptide hydrogen bonds. On the basis of the results obtained the values of relative contributions of energies of interactions of different types into the total energy of stabilization of triple helical structures were evaluated.

Key words: collagen, poly(Gly-Pro-Pro), hydration energy, enthalpy of hydrogen bonds, infrared spectroscopy.