Biopolymers and cell. Volume 20. № 4. 316-320.

T. O. Lukash, G. V. Turkovskaya, А. V. El'skaya

Restoration of the activity of higler eukaryotic aminoacyl-tRNA synthetases and their stabilization in the presence of ribosomes

Summary

The present work concerns the functional interaction between the rabbit liver ribosomes and aminoacyl-tRNA synthetases. We have shown that the ribosomes are able to stimulate the activity of leucyl-, isoleucyl- and phenylalanyl-tRNA synthetases. Possible mechanisms of this effect have been analysed. It is concluded, that the ribosomes have chaperone-like property in the maintenance of the ARS active conformation.